IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation.

Dai, Lue; Lidie, Kristy B; Chen, Qian; Adelsberger, Joseph W; Zheng, Xin; Huang, DaWei; Yang, Jun; Lempicki, Richard A; Rehman, Tauseef; Dewar, Robin L; Wang, Yanmei; Hornung, Ronald L; Canizales, Kelsey A; Lockett, Stephen J; Lane, H Clifford; Imamichi, Tomozumi

Dai, Lue; Lidie, Kristy B; Chen, Qian; Adelsberger, Joseph W; Zheng, Xin; Huang, DaWei; Yang, Jun; Lempicki, Richard A; Rehman, Tauseef; Dewar, Robin L; Wang, Yanmei; Hornung, Ronald L; Canizales, Kelsey A; Lockett, Stephen J; Lane, H Clifford; Imamichi, Tomozumi.

Affiliation

Dai L; Applied and Developmental Directorate, Science Applications International Corporation-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.

J Exp Med ; 210(3): 517-34, 2013 Mar 11.

Article in En | MEDLINE | ID: mdl-23460728

Subject(s)

Anti-HIV Agents/pharmacology; HIV-1/drug effects; Interleukins/pharmacology; Macrophages/virology; Monocytes/cytology; Spectrin/antagonists & inhibitors; Cell Differentiation/drug effects; Down-Regulation; Humans; MAP Kinase Kinase Kinases/physiology; Macrophages/cytology; Monomeric GTP-Binding Proteins/physiology; SAM Domain and HD Domain-Containing Protein 1; Spectrin/genetics; Spectrin/physiology; gag Gene Products, Human Immunodeficiency Virus/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Monocytes / HIV-1 / Interleukins / Spectrin / Anti-HIV Agents / Macrophages Limits: Humans Language: En Journal: J Exp Med Year: 2013 Document type: Article

Fulltext

XML

PubMed Links

Search on Google