Changes in brain cortex sensitivity to epileptogens under conditions of ketogenic diet.
Bull Exp Biol Med
; 154(4): 457-9, 2013 Feb.
Article
in En, Ru
| MEDLINE
| ID: mdl-23486580
ABSTRACT
The epileptogenic effects of applications of NMDA and kainic acid solutions to the frontal cortex were attenuated in rats receiving ketogenic diet (80% lipids, 3.3% carbohydrates, and 16.7% proteins) during 4 weeks. Spike latency increased, the power of focal epileptic activity decreased, and focus lifetime was shortened in these animals. Sodium benzylpenicillin and strychnine nitrate less markedly reduced epileptogenic activity.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cerebral Cortex
/
Epilepsy
/
Diet, Ketogenic
Type of study:
Diagnostic_studies
Limits:
Animals
Language:
En
/
Ru
Journal:
Bull Exp Biol Med
Year:
2013
Document type:
Article