Interleukin-27 is a potent inhibitor of cis HIV-1 replication in monocyte-derived dendritic cells via a type I interferon-independent pathway.

Chen, Qian; Swaminathan, Sanjay; Yang, De; Dai, Lue; Sui, Hongyan; Yang, Jun; Hornung, Ronald L; Wang, Yanmei; Huang, Da Wei; Hu, Xiaojun; Lempicki, Richard A; Imamichi, Tomozumi

Chen, Qian; Swaminathan, Sanjay; Yang, De; Dai, Lue; Sui, Hongyan; Yang, Jun; Hornung, Ronald L; Wang, Yanmei; Huang, Da Wei; Hu, Xiaojun; Lempicki, Richard A; Imamichi, Tomozumi.

Affiliation

Chen Q; Applied and Developmental Research Directorate (ADD), Science Application International Corporation (SAIC)-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.

PLoS One ; 8(3): e59194, 2013.

Article in En | MEDLINE | ID: mdl-23527130

Subject(s)

Dendritic Cells/metabolism; HIV-1/growth & development; Interferon Type I/metabolism; Interleukin-17/pharmacology; Virus Replication/drug effects; Blotting, Western; Cell Differentiation/immunology; Cytokines/metabolism; Dendritic Cells/cytology; Flow Cytometry; HIV-1/drug effects; Humans; Microarray Analysis; Monocytes/cytology; Monocytes/immunology; Real-Time Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Virus Replication / Dendritic Cells / Interferon Type I / HIV-1 / Interleukin-17 Limits: Humans Language: En Journal: PLoS One Year: 2013 Document type: Article

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