Complement component 3C3 and C3a receptor are required in chitin-dependent allergic sensitization to Aspergillus fumigatus but dispensable in chitin-induced innate allergic inflammation.

Roy, René M; Paes, Hugo C; Nanjappa, Som G; Sorkness, Ron; Gasper, David; Sterkel, Alana; Wüthrich, Marcel; Klein, Bruce S

Roy, René M; Paes, Hugo C; Nanjappa, Som G; Sorkness, Ron; Gasper, David; Sterkel, Alana; Wüthrich, Marcel; Klein, Bruce S.

Affiliation

Roy RM; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

mBio ; 4(2)2013 Apr 02.

Article in En | MEDLINE | ID: mdl-23549917

Subject(s)

Aspergillus fumigatus/immunology; Chitin/immunology; Complement C3/immunology; Receptors, Complement/immunology; Animals; Aspergillosis, Allergic Bronchopulmonary/immunology; Aspergillosis, Allergic Bronchopulmonary/pathology; Complement C3/genetics; Dendritic Cells/immunology; Mice; Mice, Knockout; Receptors, Complement/genetics; T-Lymphocytes/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aspergillus fumigatus / Complement C3 / Receptors, Complement / Chitin Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: MBio Year: 2013 Document type: Article

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