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Overexpression of Cdk6 and Ccnd1 in chondrocytes inhibited chondrocyte maturation and caused p53-dependent apoptosis without enhancing proliferation.
Ito, K; Maruyama, Z; Sakai, A; Izumi, S; Moriishi, T; Yoshida, C A; Miyazaki, T; Komori, H; Takada, K; Kawaguchi, H; Komori, T.
Affiliation
  • Ito K; 1] Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan [2] Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan [3] Nagasaki University Research Centre for Genomic Instability and Carcino
  • Maruyama Z; 1] Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan [2] Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
  • Sakai A; 1] Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan [2] Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Osaka University, Suita, Osaka, Japan.
  • Izumi S; Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
  • Moriishi T; Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
  • Yoshida CA; Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
  • Miyazaki T; Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
  • Komori H; Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
  • Takada K; Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Osaka University, Suita, Osaka, Japan.
  • Kawaguchi H; Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
  • Komori T; Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Oncogene ; 33(14): 1862-71, 2014 Apr 03.
Article in En | MEDLINE | ID: mdl-23624920
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Apoptosis / Chondrocytes / Cyclin D1 / Cyclin-Dependent Kinase 6 Limits: Animals / Humans Language: En Journal: Oncogene Year: 2014 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Apoptosis / Chondrocytes / Cyclin D1 / Cyclin-Dependent Kinase 6 Limits: Animals / Humans Language: En Journal: Oncogene Year: 2014 Document type: Article