Synthesis and antimicrobical evaluation of a novel class of 1,3,4-thiadiazole: derivatives bearing 1,2,4-triazolo[1,5-a]pyrimidine moiety.

Luo, Yin; Zhang, Shuai; Liu, Zhi-Jun; Chen, Wu; Fu, Jie; Zeng, Qing-Fu; Zhu, Hai-Liang

Luo, Yin; Zhang, Shuai; Liu, Zhi-Jun; Chen, Wu; Fu, Jie; Zeng, Qing-Fu; Zhu, Hai-Liang.

Affiliation

Luo Y; State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, People's Republic of China.

Eur J Med Chem ; 64: 54-61, 2013 Jun.

Article in En | MEDLINE | ID: mdl-23644188

Subject(s)

Anti-Bacterial Agents/pharmacology; Antifungal Agents/pharmacology; Bacteria/drug effects; Fungi/drug effects; Pyrimidines/pharmacology; Thiadiazoles/pharmacology; Triazoles/pharmacology; Anti-Bacterial Agents/chemical synthesis; Anti-Bacterial Agents/chemistry; Antifungal Agents/chemical synthesis; Antifungal Agents/chemistry; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Pyrimidines/chemical synthesis; Pyrimidines/chemistry; Structure-Activity Relationship; Thiadiazoles/chemical synthesis; Thiadiazoles/chemistry; Triazoles/chemical synthesis; Triazoles/chemistry

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Thiadiazoles / Bacteria / Triazoles / Fungi / Anti-Bacterial Agents / Antifungal Agents Language: En Journal: Eur J Med Chem Year: 2013 Document type: Article

Fulltext

XML

PubMed Links

Search on Google