Role of FDG PET/CT in investigating the mechanisms underlying atherosclerotic plaque formation and evolution.
Rev Esp Med Nucl Imagen Mol
; 32(4): 246-52, 2013.
Article
in En
| MEDLINE
| ID: mdl-23726249
ABSTRACT
This review article is focused on the role of FDG-PET/CT in visualizing atherosclerosis and on the relevance of inflammatory cells such as macrophages and T-lymphocytes in the formation of the atherosclerotic plaque. The vulnerability of the inflammatory plaque and the risk derived from the provocation of cardio- and cerebrovascular incidents independently from the presence of stenotic vessels are discussed as well as the evolution toward calcified plaque. The important role of FDG-PET/CT in early diagnosis of inflammatory plaque is discussed in both animal studies and in clinical setting. The possibility of curing inflammatory plaques, type of drugs, and the possibility of monitoring the anti-inflammatory treatment by FDG-PET/CT are also discussed.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tomography, X-Ray Computed
/
Radiopharmaceuticals
/
Fluorodeoxyglucose F18
/
Positron-Emission Tomography
/
Plaque, Atherosclerotic
/
Multimodal Imaging
Type of study:
Screening_studies
Limits:
Humans
Language:
En
Journal:
Rev Esp Med Nucl Imagen Mol
Year:
2013
Document type:
Article