Comparison of insulators and promoters for expression of the Wiskott-Aldrich syndrome protein using lentiviral vectors.

Koldej, Rachel M; Carney, Gael; Wielgosz, Matthew M; Zhou, Sheng; Zhan, Jun; Sorrentino, Brian P; Nienhuis, Arthur W

Koldej, Rachel M; Carney, Gael; Wielgosz, Matthew M; Zhou, Sheng; Zhan, Jun; Sorrentino, Brian P; Nienhuis, Arthur W.

Affiliation

Koldej RM; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

Hum Gene Ther Clin Dev ; 24(2): 77-85, 2013 Jun.

Article in En | MEDLINE | ID: mdl-23786330

Subject(s)

Genetic Vectors/metabolism; Lentivirus/genetics; Wiskott-Aldrich Syndrome Protein/metabolism; Wiskott-Aldrich Syndrome/therapy; Animals; B-Lymphocytes/cytology; B-Lymphocytes/metabolism; Blood Platelets/cytology; CCAAT-Enhancer-Binding Protein-alpha/genetics; CCAAT-Enhancer-Binding Protein-alpha/metabolism; Cells, Cultured; Chromatin/metabolism; Gammaretrovirus/genetics; Genetic Therapy; Genetic Vectors/genetics; Green Fluorescent Proteins/genetics; Green Fluorescent Proteins/metabolism; Humans; Leukocytes, Mononuclear/cytology; Leukocytes, Mononuclear/metabolism; Mice; Platelet Count; Promoter Regions, Genetic; Recombinant Fusion Proteins/biosynthesis; Recombinant Fusion Proteins/genetics; T-Lymphocytes/cytology; T-Lymphocytes/metabolism; Transduction, Genetic; Wiskott-Aldrich Syndrome Protein/genetics

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Wiskott-Aldrich Syndrome / Lentivirus / Wiskott-Aldrich Syndrome Protein / Genetic Vectors Limits: Animals / Humans Language: En Journal: Hum Gene Ther Clin Dev Year: 2013 Document type: Article

Fulltext

XML

PubMed Links

Search on Google