Castration; Prostatic Neoplasms/drug therapy; Humans; Immunotherapy; Male; Prostatic Neoplasms/metabolism; Prostatic Neoplasms/surgery; Prostatic Neoplasms/therapy; Receptors, Androgen/metabolism; Receptors, Growth Factor/antagonists & inhibitors

AR; Androgen receptor; Bone metastasis angiogenesis; CRPC; Castration-resistant prostate cancer; Chemotherapy; ET; Growth factor receptor inhibitors; IGF; Immunotherapy; OS; PCa; PDGFR; PFS; PSA; RANK ligand; RANK-L; Radiotherapy; SD; TKI; VEGF; VEGFR; androgen receptor; castration-resistant prostate cancer; endothelin; insulin-like growth factor; overall survival; platelet-derived growth factor receptor; progression free survival; prostate cancer; prostate-specific antigen; stable disease; tyrosine kinase inhibitor; vascular endothelial growth factor; vascular endothelial growth factor receptor