Analysis of the genomic response of human prostate cancer cells to histone deacetylase inhibitors.

Kortenhorst, Madeleine S Q; Wissing, Michel D; Rodríguez, Ronald; Kachhap, Sushant K; Jans, Judith J M; Van der Groep, Petra; Verheul, Henk M W; Gupta, Anuj; Aiyetan, Paul O; van der Wall, Elsken; Carducci, Michael A; Van Diest, Paul J; Marchionni, Luigi

Kortenhorst, Madeleine S Q; Wissing, Michel D; Rodríguez, Ronald; Kachhap, Sushant K; Jans, Judith J M; Van der Groep, Petra; Verheul, Henk M W; Gupta, Anuj; Aiyetan, Paul O; van der Wall, Elsken; Carducci, Michael A; Van Diest, Paul J; Marchionni, Luigi.

Affiliation

Kortenhorst MS; Department of Gynecology; Catharina Hospital Eindhoven; Eindhoven, The Netherlands; Prostate Cancer Program; Sidney Kimmel Comprehensive Cancer Center; Johns Hopkins University School of Medicine; Baltimore, MD USA; These authors contributed equally to this work.

Epigenetics ; 8(9): 907-20, 2013 Sep.

Article in En | MEDLINE | ID: mdl-23880963

Subject(s)

Histone Deacetylase Inhibitors/pharmacology; Histone Deacetylases/metabolism; Hydroxamic Acids/pharmacology; Prostatic Neoplasms/genetics; Valproic Acid/pharmacology; Cell Line, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic/drug effects; Genome, Human; Histone Deacetylase Inhibitors/therapeutic use; Histone Deacetylases/genetics; Humans; Hydroxamic Acids/therapeutic use; M Phase Cell Cycle Checkpoints/genetics; Major Histocompatibility Complex/genetics; Male; Microarray Analysis; Prostatic Neoplasms/drug therapy; Signal Transduction/drug effects; Valproic Acid/therapeutic use; Vorinostat

Key words

HDACis; analysis of functional annotation; gene expression analysis; major histocompatibility complex; mitotic spindle checkpoint; prostate cancer; valproic acid; vorinostat

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Valproic Acid / Histone Deacetylase Inhibitors / Histone Deacetylases / Hydroxamic Acids Type of study: Prognostic_studies Limits: Humans / Male Language: En Journal: Epigenetics Year: 2013 Document type: Article

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