Small interfering RNA targeting nuclear factor kappa B to prevent vein graft stenosis in rat models.

Meng, X B; Bi, X L; Zhao, H L; Feng, J B; Zhang, J P; Song, G M; Sun, W Y; Bi, Y W

Meng, X B; Bi, X L; Zhao, H L; Feng, J B; Zhang, J P; Song, G M; Sun, W Y; Bi, Y W.

Affiliation

Meng XB; Department of Cardiovascular Surgery, QiLu Hospital, Shandong University, Jinan, Shandong Province, China.

Transplant Proc ; 45(6): 2553-8, 2013.

Article in En | MEDLINE | ID: mdl-23953580

Subject(s)

Genetic Therapy/methods; Graft Occlusion, Vascular/prevention & control; Jugular Veins/transplantation; NF-kappa B/metabolism; RNA Interference; RNA, Small Interfering/metabolism; Animals; Cell Proliferation; Chemokine CCL2/genetics; Chemokine CCL2/metabolism; Constriction, Pathologic; Disease Models, Animal; Gene Expression Regulation; Graft Occlusion, Vascular/etiology; Graft Occlusion, Vascular/genetics; Graft Occlusion, Vascular/metabolism; Graft Occlusion, Vascular/pathology; Hyperplasia; Jugular Veins/metabolism; Jugular Veins/pathology; Ki-67 Antigen/metabolism; Male; NF-kappa B/genetics; Neointima; RNA, Messenger/metabolism; Rats; Rats, Sprague-Dawley; Transcription Factor RelA/genetics; Transcription Factor RelA/metabolism; Transfection; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / NF-kappa B / RNA, Small Interfering / RNA Interference / Graft Occlusion, Vascular / Jugular Veins Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Transplant Proc Year: 2013 Document type: Article

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