[In vitro spermatogenesis
new horizon to restore fertility?]. / Spermatogenèse in vitro
nouvel horizon pour restaurer la fertilité ?
Gynecol Obstet Fertil
; 41(9): 548-50, 2013 Sep.
Article
in Fr
| MEDLINE
| ID: mdl-23972917
ABSTRACT
The survival of the young boy after cancer has considerably progressed in recent years due to the efficiency of chemo/radiotherapy against the tumor cells. However, this treatment causes adverse effects on healthy tissues, including fertility. Freezing testicular tissue before highly gonadotoxic treatment is a prerequisite for preserving fertility in prepubertal boys that do not produce sperm yet. But which strategy proposes to restore fertility from frozen-thawed testicular tissue? One potential solution would be to consider an in vitro maturation of spermatogonial stem cells. In this article we trace the chronological development of in vitro spermatogenesis that resulted in mouse sperm production in vitro and give an overview of new challenges for the future.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Spermatogenesis
/
Adult Stem Cells
/
Fertility Preservation
Limits:
Animals
Language:
Fr
Journal:
Gynecol Obstet Fertil
Year:
2013
Document type:
Article