Enhanced purinergic contractile responses and P2X1 receptor expression in detrusor muscle during cycles of hypoxia-glucopenia and reoxygenation.

Elliott, R A; Tonnu, A; Ghaffar, N; Taylor, A H; Tincello, D G; Norman, R I

Elliott, R A; Tonnu, A; Ghaffar, N; Taylor, A H; Tincello, D G; Norman, R I.

Affiliation

Elliott RA; R. A. Elliott: University of Leicester, Cancer Studies and Molecular Medicine, Reproductive Sciences Section, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK. rae5@leicester.ac.uk.

Exp Physiol ; 98(12): 1683-95, 2013 Dec.

Article in En | MEDLINE | ID: mdl-23975903

Subject(s)

Glucose/metabolism; Muscle Contraction/physiology; Muscle, Smooth/physiology; Oxygen/metabolism; Receptors, Purinergic P2X1/metabolism; Urinary Bladder/physiology; Acetylcholine/metabolism; Adenosine Triphosphate/metabolism; Animals; Atropine/pharmacology; Cell Membrane/metabolism; Dose-Response Relationship, Drug; Electric Stimulation; Female; Fluorescent Antibody Technique; Hypoxia/metabolism; In Vitro Techniques; Male; Purinergic P2X Receptor Antagonists/pharmacology; Rats; Rats, Wistar; Tissue Distribution

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / Urinary Bladder / Receptors, Purinergic P2X1 / Glucose / Muscle Contraction / Muscle, Smooth Limits: Animals Language: En Journal: Exp Physiol Year: 2013 Document type: Article

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