Repression of miR-126 and upregulation of adrenomedullin in the stromal endothelium by cancer-stromal cross talks confers angiogenesis of cervical cancer.

Huang, T-H; Chu, T-Y

Huang, T-H; Chu, T-Y.

Affiliation

Huang TH; 1] Center for Cervical Cancer Prevention, Department of Research, Tzu Chi General Hospital, Hualien, Taiwan, ROC [2] Institute of Medical Science, Tzu Chi University, Hualien, Taiwan, ROC.
Chu TY; 1] Center for Cervical Cancer Prevention, Department of Research, Tzu Chi General Hospital, Hualien, Taiwan, ROC [2] Institute of Medical Science, Tzu Chi University, Hualien, Taiwan, ROC [3] Department of Obstetrics and Gynecology, Tzu Chi General Hospital, Tzu Chi University, Hualien, Taiwan, ROC.

Oncogene ; 33(28): 3636-47, 2014 Jul 10.

Article in En | MEDLINE | ID: mdl-24037526

Subject(s)

Adrenomedullin/biosynthesis; Down-Regulation; MicroRNAs/genetics; Neovascularization, Pathologic; Stromal Cells/metabolism; Up-Regulation; Uterine Cervical Neoplasms/blood supply; Uterine Cervical Neoplasms/pathology; Adrenomedullin/genetics; Adrenomedullin/metabolism; Animals; Carcinoma in Situ/blood supply; Carcinoma in Situ/genetics; Carcinoma in Situ/pathology; Cell Communication; Cell Proliferation; Cell Transformation, Neoplastic; Endothelium/pathology; Female; Fibroblasts/pathology; Human Umbilical Vein Endothelial Cells/cytology; Human Umbilical Vein Endothelial Cells/metabolism; Humans; Mice; Neoplasm Invasiveness; Stromal Cells/pathology; Uterine Cervical Neoplasms/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Down-Regulation / Up-Regulation / Uterine Cervical Neoplasms / Stromal Cells / MicroRNAs / Adrenomedullin / Neovascularization, Pathologic Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Oncogene Year: 2014 Document type: Article

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