[Therapy refractory stromal Herpes keratitis under aciclovir].

Spira, C; Szentmáry, N; Hasenfus, A; Sauter, M; Smola, S; Seitz, B

[Therapy refractory stromal Herpes keratitis under aciclovir]. / Therapierefraktäre stromale Herpeskeratitis unter Aciclovir.

Spira, C; Szentmáry, N; Hasenfus, A; Sauter, M; Smola, S; Seitz, B.

Affiliation

Spira C; Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Kirrberger Str. 100, Gebäude 22, 66424, Homburg/Saar, Deutschland, corinna.spira@uks.eu.

Ophthalmologe ; 111(7): 654-9, 2014.

Article in De | MEDLINE | ID: mdl-24046171

ABSTRACT

ABSTRACT

We report the case of a patient with suspected ulcerating necrotizing herpetic stromal keratitis who showed no improvement despite intensive (amongst others antiherpetic) topical and systemic therapy. The ulcer healed following amniotic membrane transplantation and penetrating excimer laser keratoplasty was performed to improve visual acuity. The excision showed deep stromal proof of herpes simplex virus (HSV) type 1 antigens.

Subject(s)

Acyclovir/therapeutic use; Amnion/transplantation; Biological Dressings; Keratitis, Herpetic/pathology; Keratitis, Herpetic/surgery; Keratoplasty, Penetrating/methods; Laser Therapy/methods; Aged; Antiviral Agents/therapeutic use; Combined Modality Therapy/methods; Humans; Male; Treatment Failure; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Dressings / Acyclovir / Keratoplasty, Penetrating / Keratitis, Herpetic / Laser Therapy / Amnion Limits: Aged / Humans / Male Language: De Journal: Ophthalmologe Year: 2014 Document type: Article

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