A phase II study of an investigational tetravalent influenza vaccine formulation combining MF59®: adjuvanted, pre-pandemic, A/H5N1 vaccine and trivalent seasonal influenza vaccine in healthy adults.

Herbinger, Karl-Heinz; von Sonnenburg, Frank; Nothdurft, Hans Dieter; Perona, Pamela; Borkowski, Astrid; Fragapane, Elena; Nicolay, Uwe; Clemens, Ralf

Herbinger, Karl-Heinz; von Sonnenburg, Frank; Nothdurft, Hans Dieter; Perona, Pamela; Borkowski, Astrid; Fragapane, Elena; Nicolay, Uwe; Clemens, Ralf.

Affiliation

Herbinger KH; Department of Infectious Diseases and Tropical Medicine; University Hospital; Ludwig-Maximilians-Universität München; Munich, Germany.
von Sonnenburg F; Department of Infectious Diseases and Tropical Medicine; University Hospital; Ludwig-Maximilians-Universität München; Munich, Germany.
Nothdurft HD; Department of Infectious Diseases and Tropical Medicine; University Hospital; Ludwig-Maximilians-Universität München; Munich, Germany.
Perona P; Department of Infectious Diseases and Tropical Medicine; University Hospital; Ludwig-Maximilians-Universität München; Munich, Germany.
Borkowski A; Novartis Vaccines & Diagnostics; Cambridge, MA USA.
Fragapane E; Novartis Vaccines & Diagnostics; Cambridge, MA USA.
Nicolay U; Novartis Vaccines & Diagnostics; Cambridge, MA USA.
Clemens R; Novartis Vaccines & Diagnostics; Cambridge, MA USA.

Hum Vaccin Immunother ; 10(1): 92-9, 2014.

Article in En | MEDLINE | ID: mdl-24047817

Subject(s)

Adjuvants, Immunologic/administration & dosage; Influenza A Virus, H1N1 Subtype/immunology; Influenza A Virus, H3N2 Subtype/immunology; Influenza A Virus, H5N1 Subtype/immunology; Influenza B virus/immunology; Influenza Vaccines/immunology; Polysorbates/administration & dosage; Squalene/administration & dosage; Adjuvants, Immunologic/adverse effects; Adolescent; Adult; Antibodies, Viral/blood; Drug-Related Side Effects and Adverse Reactions/epidemiology; Drug-Related Side Effects and Adverse Reactions/pathology; Female; Healthy Volunteers; Hemagglutination Inhibition Tests; Humans; Influenza Vaccines/administration & dosage; Influenza Vaccines/adverse effects; Male; Middle Aged; Neutralization Tests; Polysorbates/adverse effects; Squalene/adverse effects; Young Adult

Key words

H5N1; MF59; influenza vaccine; pandemic; seasonal influenza

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Influenza B virus / Polysorbates / Squalene / Influenza Vaccines / Adjuvants, Immunologic / Influenza A Virus, H1N1 Subtype / Influenza A Virus, H3N2 Subtype / Influenza A Virus, H5N1 Subtype Type of study: Clinical_trials / Observational_studies Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Language: En Journal: Hum Vaccin Immunother Year: 2014 Document type: Article

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