Nitric oxide signaling contributes to ectopic orofacial neuropathic pain.

Sugiyama, T; Shinoda, M; Watase, T; Honda, K; Ito, R; Kaji, K; Urata, K; Lee, J; Ohara, K; Takahashi, O; Echizenya, S; Iwata, K

Sugiyama, T; Shinoda, M; Watase, T; Honda, K; Ito, R; Kaji, K; Urata, K; Lee, J; Ohara, K; Takahashi, O; Echizenya, S; Iwata, K.

Affiliation

Sugiyama T; Department of Oral Histology, Kanagawa Dental College, 82 Inaoka-cho, Yokosuka, 238-8580, Japan.

J Dent Res ; 92(12): 1113-7, 2013 Dec.

Article in En | MEDLINE | ID: mdl-24130220

Subject(s)

Facial Pain/etiology; Mandibular Nerve/physiopathology; Neuralgia/etiology; Nitric Oxide/physiology; Signal Transduction/physiology; Trigeminal Nerve Injuries/complications; Animals; Arginine/analogs & derivatives; Arginine/pharmacology; Enzyme Inhibitors/pharmacology; Enzyme Precursors/pharmacology; Hyperalgesia/etiology; Indazoles/pharmacology; Lip/innervation; Male; Mandibular Nerve/pathology; Neural Pathways/pathology; Neural Pathways/physiopathology; Neurons/drug effects; Neurons/pathology; Nitric Oxide/analysis; Nitric Oxide Synthase/antagonists & inhibitors; Nitric Oxide Synthase Type I/analysis; Nitric Oxide Synthase Type I/antagonists & inhibitors; Pain Threshold/physiology; Rats; Rats, Sprague-Dawley; Sensory Thresholds/physiology; Signal Transduction/drug effects; Touch/physiology; Trigeminal Ganglion/drug effects; Trigeminal Ganglion/pathology

Key words

7-nitroindazole; L-arginine; infraorbital nerve injury; mechanical allodynia; nitric oxide synthase; trigeminal ganglion

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Facial Pain / Signal Transduction / Trigeminal Nerve Injuries / Mandibular Nerve / Neuralgia / Nitric Oxide Type of study: Etiology_studies Limits: Animals Language: En Journal: J Dent Res Year: 2013 Document type: Article

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