Proteinase-activated receptor-2 activation participates in allergic sensitization to house dust mite allergens in a murine model.

Davidson, C E; Asaduzzaman, M; Arizmendi, N G; Polley, D; Wu, Y; Gordon, J R; Hollenberg, M D; Cameron, L; Vliagoftis, H

Davidson, C E; Asaduzzaman, M; Arizmendi, N G; Polley, D; Wu, Y; Gordon, J R; Hollenberg, M D; Cameron, L; Vliagoftis, H.

Affiliation

Davidson CE; Pulmonary Research Group, Department of Medicine, University of Alberta, Edmonton, AB, Canada.

Clin Exp Allergy ; 43(11): 1274-85, 2013 Nov.

Article in En | MEDLINE | ID: mdl-24152160

Subject(s)

Allergens/immunology; Hypersensitivity/immunology; Hypersensitivity/metabolism; Pyroglyphidae/immunology; Receptor, PAR-2/metabolism; Animals; CD4-Positive T-Lymphocytes/immunology; CD4-Positive T-Lymphocytes/metabolism; Cytokines/metabolism; Disease Models, Animal; Hypersensitivity/genetics; Immunoglobulin G/blood; Immunoglobulin G/immunology; Inflammation/genetics; Inflammation/immunology; Inflammation/metabolism; Lung/immunology; Lung/metabolism; Lung/pathology; Lymphocyte Activation/immunology; Male; Mice; Mice, Knockout; Receptor, PAR-2/antagonists & inhibitors; Receptor, PAR-2/genetics; Spleen/cytology; Spleen/immunology; Th2 Cells/immunology; Th2 Cells/metabolism

Key words

allergic airway inflammation; allergic sensitization, CD4 lymphocytes; house dust mites; proteinase-activated receptor-2

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Allergens / Pyroglyphidae / Receptor, PAR-2 / Hypersensitivity Limits: Animals Language: En Journal: Clin Exp Allergy Year: 2013 Document type: Article

Fulltext

XML

PubMed Links

Search on Google