The role of alpha-2 adrenoceptor subtype in the antiallodynic effect of intraplantar dexmedetomidine in a rat spinal nerve ligation model.

Lee, Hyung Gon; Choi, Jeong Il; Kim, Yeo Ok; Yoon, Myung Ha

Lee, Hyung Gon; Choi, Jeong Il; Kim, Yeo Ok; Yoon, Myung Ha.

Affiliation

Lee HG; Department of Anesthesiology and Pain Medicine, Chonnam National University, Medical School, Gwangju, Republic of Korea.

Neurosci Lett ; 557 Pt B: 118-22, 2013 Dec 17.

Article in En | MEDLINE | ID: mdl-24161890

Subject(s)

Adrenergic alpha-2 Receptor Agonists/pharmacology; Dexmedetomidine/pharmacology; Hyperalgesia/metabolism; Neuralgia/metabolism; Receptors, Adrenergic, alpha-2/metabolism; Analgesics, Non-Narcotic/pharmacology; Animals; Axotomy; Disease Models, Animal; Ligation; Male; Rats; Rats, Sprague-Dawley; Spinal Nerves/metabolism; Spinal Nerves/surgery

Key words

Adrenoceptors; Antiallodynia; Dexmedetomidine; Neuropathic pain; Peripheral

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Adrenergic, alpha-2 / Dexmedetomidine / Adrenergic alpha-2 Receptor Agonists / Hyperalgesia / Neuralgia Limits: Animals Language: En Journal: Neurosci Lett Year: 2013 Document type: Article

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