Production of the first effective hyperimmune equine serum antivenom against Africanized bees.

Santos, Keity Souza; Stephano, Marco Antonio; Marcelino, José Roberto; Ferreira, Virginia Maria Resende; Rocha, Thalita; Caricati, Celso; Higashi, Hisako Gondo; Moro, Ana Maria; Kalil, Jorge Elias; Malaspina, Osmar; Castro, Fabio Fernandes Morato; Palma, Mário Sérgio

Santos, Keity Souza; Stephano, Marco Antonio; Marcelino, José Roberto; Ferreira, Virginia Maria Resende; Rocha, Thalita; Caricati, Celso; Higashi, Hisako Gondo; Moro, Ana Maria; Kalil, Jorge Elias; Malaspina, Osmar; Castro, Fabio Fernandes Morato; Palma, Mário Sérgio.

Affiliation

Santos KS; Division of Clinical Immunology and Allergy, University of São Paulo School of Medicine, FMUSP, São Paulo, Brazil ; Institute for Investigation in Immunology-INCT, São Paulo, SP, Brazil ; Heart Institute (InCor), LIM-19, University of São Paulo School of Medicine, São Paulo, SP, Brazil.

PLoS One ; 8(11): e79971, 2013.

Article in En | MEDLINE | ID: mdl-24236166

Subject(s)

Antivenins/immunology; Bee Venoms/immunology; Bees/immunology; Animals; Antibodies, Neutralizing/immunology; Antivenins/toxicity; Dose-Response Relationship, Immunologic; Hemolysis/immunology; Horses; Immunization; Immunoglobulin Fab Fragments/immunology; Immunoglobulin Fab Fragments/isolation & purification; Immunoglobulin G/immunology; Male; Mice; Neutralization Tests

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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Bee Venoms / Bees / Antivenins Limits: Animals Language: En Journal: PLoS One Year: 2013 Document type: Article

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