Copy number genome alterations are associated with treatment response and outcome in relapsed childhood ETV6/RUNX1-positive acute lymphoblastic leukemia.

Bokemeyer, Almut; Eckert, Cornelia; Meyr, Franziska; Koerner, Gabriele; von Stackelberg, Arend; Ullmann, Reinhard; Türkmen, Seval; Henze, Günter; Seeger, Karl

Bokemeyer, Almut; Eckert, Cornelia; Meyr, Franziska; Koerner, Gabriele; von Stackelberg, Arend; Ullmann, Reinhard; Türkmen, Seval; Henze, Günter; Seeger, Karl.

Affiliation

Bokemeyer A; karl.seeger@charite.de.

Haematologica ; 99(4): 706-14, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24241490

Subject(s)

Core Binding Factor Alpha 2 Subunit/genetics; DNA Copy Number Variations; Oncogene Proteins, Fusion/genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology; B-Lymphocytes/metabolism; B-Lymphocytes/pathology; Bone Marrow/metabolism; Bone Marrow/pathology; Cell Differentiation; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 5; Chromosomes, Human, X; Female; Follow-Up Studies; Humans; Male; Neoplasm Recurrence, Local; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma/mortality; Prognosis; Remission Induction; Sex Factors; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oncogene Proteins, Fusion / Core Binding Factor Alpha 2 Subunit / Precursor Cell Lymphoblastic Leukemia-Lymphoma / DNA Copy Number Variations Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Haematologica Year: 2014 Document type: Article

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