Correlation between endogenous VWF:Ag and PK parameters and bleeding frequency in severe haemophilia A subjects during three-times-weekly prophylaxis with rFVIII-FS.

Lalezari, S; Martinowitz, U; Windyga, J; Enriquez, M M; Delesen, H; Schwartz, L; Scharrer, I

Lalezari, S; Martinowitz, U; Windyga, J; Enriquez, M M; Delesen, H; Schwartz, L; Scharrer, I.

Affiliation

Lalezari S; National Hemophilia Center, Chaim Sheba Medical Center, Tel Hashomer, Israel.

Haemophilia ; 20(1): e15-22, 2014 Jan.

Article in En | MEDLINE | ID: mdl-24252058

Subject(s)

Factor VIII/therapeutic use; Hemophilia A/blood; Hemophilia A/drug therapy; Hemorrhage/metabolism; Premedication; Sucrose/therapeutic use; von Willebrand Factor/metabolism; Adolescent; Adult; Age Factors; Aged; Blood Coagulation Tests; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Factor VIII/administration & dosage; Hemorrhage/blood; Hemorrhage/etiology; Humans; Male; Middle Aged; Severity of Illness Index; Sucrose/administration & dosage; Treatment Outcome; Young Adult; von Willebrand Factor/immunology

Key words

age; factor VIII; pharmacokinetics; von Willebrand factor

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Full text: 1 Collection: 01-internacional Topics: Promover_ampliacao_atencao_especializada Database: MEDLINE Main subject: Premedication / Sucrose / Factor VIII / Von Willebrand Factor / Hemophilia A / Hemorrhage Type of study: Clinical_trials / Etiology_studies Aspects: Patient_preference Limits: Adolescent / Adult / Aged / Humans / Male / Middle aged Language: En Journal: Haemophilia Year: 2014 Document type: Article

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