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PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors.
Martínez-Díez, Marta; Guillén-Navarro, María José; Pera, Benet; Bouchet, Benjamin Pierre; Martínez-Leal, Juan Fernando; Barasoain, Isabel; Cuevas, Carmen; Andreu, Jose M; García-Fernández, Luis Francisco; Díaz, J Fernando; Avilés, Pablo; Galmarini, Carlos M.
Affiliation
  • Martínez-Díez M; PharmaMar S.A., Avda de los Reyes 1, Polígono Industrial La Mina, Colmenar Viejo, 28770 Madrid, Spain.
  • Guillén-Navarro MJ; PharmaMar S.A., Avda de los Reyes 1, Polígono Industrial La Mina, Colmenar Viejo, 28770 Madrid, Spain.
  • Pera B; Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.
  • Bouchet BP; Centre Léon Bérard, Lyon F-69373, France.
  • Martínez-Leal JF; PharmaMar S.A., Avda de los Reyes 1, Polígono Industrial La Mina, Colmenar Viejo, 28770 Madrid, Spain.
  • Barasoain I; Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.
  • Cuevas C; PharmaMar S.A., Avda de los Reyes 1, Polígono Industrial La Mina, Colmenar Viejo, 28770 Madrid, Spain.
  • Andreu JM; Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.
  • García-Fernández LF; PharmaMar S.A., Avda de los Reyes 1, Polígono Industrial La Mina, Colmenar Viejo, 28770 Madrid, Spain.
  • Díaz JF; Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain.
  • Avilés P; PharmaMar S.A., Avda de los Reyes 1, Polígono Industrial La Mina, Colmenar Viejo, 28770 Madrid, Spain.
  • Galmarini CM; PharmaMar S.A., Avda de los Reyes 1, Polígono Industrial La Mina, Colmenar Viejo, 28770 Madrid, Spain. Electronic address: cgalmarini@pharmamar.com.
Biochem Pharmacol ; 88(3): 291-302, 2014 Apr 01.
Article in En | MEDLINE | ID: mdl-24486569
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrones / ATP Binding Cassette Transporter, Subfamily B, Member 1 / Tubulin Modulators / Polyketides / Antineoplastic Agents Limits: Animals Language: En Journal: Biochem Pharmacol Year: 2014 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrones / ATP Binding Cassette Transporter, Subfamily B, Member 1 / Tubulin Modulators / Polyketides / Antineoplastic Agents Limits: Animals Language: En Journal: Biochem Pharmacol Year: 2014 Document type: Article