Creatin-kinase elevation after accidental ingestion of almotriptan in an 18-month-old girl.
Minerva Pediatr
; 66(1): 95-7, 2014 Feb.
Article
in En
| MEDLINE
| ID: mdl-24608586
ABSTRACT
Few studies have been published to demonstrate tolerability and efficacy of almotriptan in adolescents and children with migraine, particularly in the first years of life, though preliminary results are favorable. We report the case of an 18-month-old infant with elevation of serum levels of creatin-kinase after the accidental ingestion of almotriptan. A previously healthy 18-month-old girl (weight 13 kg) was admitted to our Department four hours after the accidental ingestion of 6.25 mg of almotriptan (0.48 mg/kg), without any specific symptom. The performed investigations showed high serum levels of creatin-kinase (CK) (527 IU/L; normal values 24-170 IU/L). Transaminase, creatinine, aldolase, myoglobin and troponin T serum levels were normal. The electrocardiogram proved negative. Initial management consisted of parenteral rehydration with saline solution. CK levels lowered significantly at 12 hours (455 IU/L) and at 65 hours (188 IU/L) after the ingestion. No symptoms were observed before discharge and on follow-up.
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Collection:
01-internacional
Health context:
3_ND
Database:
MEDLINE
Main subject:
Tryptamines
/
Serotonin Receptor Agonists
/
Creatine Kinase
Limits:
Female
/
Humans
/
Infant
Language:
En
Journal:
Minerva Pediatr
Year:
2014
Document type:
Article