The effect of types I and III interferons on adrenocortical cells and its possible implications for autoimmune Addison's disease.

Hellesen, A; Edvardsen, K; Breivik, L; Husebye, E S; Bratland, E

Hellesen, A; Edvardsen, K; Breivik, L; Husebye, E S; Bratland, E.

Affiliation

Hellesen A; Section for Endocrinology, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Medicine, Haukeland University Hospital, Bergen, Norway.

Clin Exp Immunol ; 176(3): 351-62, 2014 Jun.

Article in En | MEDLINE | ID: mdl-24666275

Subject(s)

Addison Disease/immunology; Addison Disease/metabolism; Adrenal Cortex/cytology; Adrenal Cortex/metabolism; Interferons/metabolism; Addison Disease/genetics; Adrenal Cortex/drug effects; Cell Line; Cell Movement/drug effects; Cell Movement/immunology; Chemokines/metabolism; Drug Synergism; Gene Expression; Gene Expression Regulation/drug effects; Histocompatibility Antigens Class I/genetics; Histocompatibility Antigens Class I/immunology; Humans; Interferons/pharmacology; Interferons/toxicity; Poly I-C/pharmacology; Receptors, Interferon/genetics; Receptors, Interferon/metabolism; Steroid 21-Hydroxylase/genetics; Steroid 21-Hydroxylase/metabolism; T-Lymphocyte Subsets/drug effects; T-Lymphocyte Subsets/immunology; Toll-Like Receptor 3/metabolism

Key words

21-hydroxylase; Addison's disease; CXC chemokine ligand 10; interferon; polyinosine-polycytidylic acid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Addison Disease / Interferons / Adrenal Cortex Limits: Humans Language: En Journal: Clin Exp Immunol Year: 2014 Document type: Article

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