N-type calcium current, Cav2.2, is enhanced in small-diameter sensory neurons isolated from Nf1+/- mice.

Duan, J-H; Hodgdon, K E; Hingtgen, C M; Nicol, G D

Duan, J-H; Hodgdon, K E; Hingtgen, C M; Nicol, G D.

Affiliation

Duan JH; Department of Pharmacology & Toxicology, School of Medicine, Indiana University, Indianapolis, IN 46202, USA.
Hodgdon KE; Department of Pharmacology & Toxicology, School of Medicine, Indiana University, Indianapolis, IN 46202, USA.
Hingtgen CM; Department of Pharmacology & Toxicology, School of Medicine, Indiana University, Indianapolis, IN 46202, USA; Department of Neurology, School of Medicine, Indiana University, Indianapolis, IN 46202, USA.
Nicol GD; Department of Pharmacology & Toxicology, School of Medicine, Indiana University, Indianapolis, IN 46202, USA. Electronic address: gnicol@iupui.edu.

Neuroscience ; 270: 192-202, 2014 Jun 13.

Article in En | MEDLINE | ID: mdl-24755485

Subject(s)

Calcium Channels, N-Type/metabolism; Calcium/metabolism; Neurofibromin 1/metabolism; Sensory Receptor Cells/physiology; Animals; Calcium Channel Blockers/pharmacology; Calcium Channels/metabolism; Calcium Channels, L-Type/metabolism; Capsaicin/pharmacology; Cells, Cultured; Ganglia, Spinal/drug effects; Ganglia, Spinal/physiology; Mice, Inbred C57BL; Mice, Transgenic; Neurofibromin 1/genetics; Patch-Clamp Techniques; RNA, Messenger/metabolism; Real-Time Polymerase Chain Reaction; Sensory Receptor Cells/drug effects; Sensory System Agents/pharmacology

Key words

calcium channels; dorsal root ganglia; mRNA; neurofibromatosis; qPCR

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sensory Receptor Cells / Calcium / Calcium Channels, N-Type / Neurofibromin 1 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Neuroscience Year: 2014 Document type: Article

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