A novel method for direct measurement of complement convertases activity in human serum.

Blom, A M; Volokhina, E B; Fransson, V; Strömberg, P; Berghard, L; Viktorelius, M; Mollnes, T E; López-Trascasa, M; van den Heuvel, L P; Goodship, T H; Marchbank, K J; Okroj, M

Blom, A M; Volokhina, E B; Fransson, V; Strömberg, P; Berghard, L; Viktorelius, M; Mollnes, T E; López-Trascasa, M; van den Heuvel, L P; Goodship, T H; Marchbank, K J; Okroj, M.

Affiliation

Blom AM; Department of Laboratory Medicine Malmö, Lund University, Malmö, Sweden.

Clin Exp Immunol ; 178(1): 142-53, 2014 Oct.

Article in En | MEDLINE | ID: mdl-24853370

Subject(s)

Complement C3-C5 Convertases/analysis; Erythrocytes/enzymology; Immunoassay/methods; Animals; Autoantibodies/immunology; Complement C3 Nephritic Factor/immunology; Complement C3-C5 Convertases/immunology; Complement Pathway, Alternative/immunology; Complement System Proteins/immunology; Erythrocytes/immunology; Guinea Pigs; Half-Life; Humans; Rabbits; Sheep

Key words

OmCI; complement system; convertase; eculizumab

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoassay / Erythrocytes / Complement C3-C5 Convertases Limits: Animals / Humans Language: En Journal: Clin Exp Immunol Year: 2014 Document type: Article

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