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Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma.
Green, Michael R; Vicente-Dueñas, Carolina; Romero-Camarero, Isabel; Long Liu, Chih; Dai, Bo; González-Herrero, Inés; García-Ramírez, Idoia; Alonso-Escudero, Esther; Iqbal, Javeed; Chan, Wing C; Campos-Sanchez, Elena; Orfao, Alberto; Pintado, Belén; Flores, Teresa; Blanco, Oscar; Jiménez, Rafael; Martínez-Climent, Jose Angel; Criado, Francisco Javier García; Cenador, María Begoña García; Zhao, Shuchun; Natkunam, Yasodha; Lossos, Izidore S; Majeti, Ravindra; Melnick, Ari; Cobaleda, César; Alizadeh, Ash A; Sánchez-García, Isidro.
Affiliation
  • Green MR; 1] Divisions of Oncology and Hematology, Department of Medicine, School of Medicine, Stanford University, Stanford, California 94305, USA [2].
  • Vicente-Dueñas C; 1] Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Campus M. de Unamuno s/n, 37007 Salamanca, Spain [2] Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain [3].
  • Romero-Camarero I; 1] Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Campus M. de Unamuno s/n, 37007 Salamanca, Spain [2] Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
  • Long Liu C; Divisions of Oncology and Hematology, Department of Medicine, School of Medicine, Stanford University, Stanford, California 94305, USA.
  • Dai B; Divisions of Oncology and Hematology, Department of Medicine, School of Medicine, Stanford University, Stanford, California 94305, USA.
  • González-Herrero I; 1] Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Campus M. de Unamuno s/n, 37007 Salamanca, Spain [2] Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
  • García-Ramírez I; 1] Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Campus M. de Unamuno s/n, 37007 Salamanca, Spain [2] Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
  • Alonso-Escudero E; 1] Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Campus M. de Unamuno s/n, 37007 Salamanca, Spain [2] Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain.
  • Iqbal J; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.
  • Chan WC; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.
  • Campos-Sanchez E; Centro de Biología Molecular Severo Ochoa, CSIC/Universidad Autónoma de Madrid, c/Nicolás Cabrera, n° 1, Campus de Cantoblanco, 28049 Madrid, Spain.
  • Orfao A; Servicio de Citometría and Departamento de Medicina, Universidad de Salamanca, 37007 Salamanca, Spain.
  • Pintado B; Genetically Engineered Mouse Facility, CNB-CSIC, 28006 Madrid, Spain.
  • Flores T; 1] Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain [2] Departamento de Anatomía Patológica, Universidad de Salamanca, 37007 Salamanca, Spain.
  • Blanco O; Departamento de Anatomía Patológica, Universidad de Salamanca, 37007 Salamanca, Spain.
  • Jiménez R; 1] Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain [2] Departamento de Fisiología y Farmacología, Universidad de Salamanca, Campus M. Unamuno s/n, 37007 Salamanca, Spain.
  • Martínez-Climent JA; Division of Oncology, Center for Applied Medical Research (CIMA), University of Navarra, 31008 Pamplona, Spain.
  • Criado FJ; Departamento de Cirugía, Universidad de Salamanca, 37007 Salamanca, Spain.
  • Cenador MB; Departamento de Cirugía, Universidad de Salamanca, 37007 Salamanca, Spain.
  • Zhao S; Department of Pathology, Stanford University School of Medicine, Stanford, California, 94305 USA.
  • Natkunam Y; Department of Pathology, Stanford University School of Medicine, Stanford, California, 94305 USA.
  • Lossos IS; Division of Hematology-Oncology, University of Miami, Sylvester Comprehensive Cancer Center, Miami, Florida 33136, USA.
  • Majeti R; Divisions of Oncology and Hematology, Department of Medicine, School of Medicine, Stanford University, Stanford, California 94305, USA.
  • Melnick A; Departments of Medicine and Pharmacology, Weill Cornell Medical College, New York, New York 10021, USA.
  • Cobaleda C; Centro de Biología Molecular Severo Ochoa, CSIC/Universidad Autónoma de Madrid, c/Nicolás Cabrera, n° 1, Campus de Cantoblanco, 28049 Madrid, Spain.
  • Alizadeh AA; 1] Divisions of Oncology and Hematology, Department of Medicine, School of Medicine, Stanford University, Stanford, California 94305, USA [2].
  • Sánchez-García I; 1] Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC/Universidad de Salamanca, Campus M. de Unamuno s/n, 37007 Salamanca, Spain [2] Institute of Biomedical Research of Salamanca (IBSAL), 37007 Salamanca, Spain [3].
Nat Commun ; 5: 3904, 2014 Jun 02.
Article in En | MEDLINE | ID: mdl-24887457
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / B-Lymphocytes / Gene Expression Regulation, Neoplastic / Lymphoma, Large B-Cell, Diffuse / DNA-Binding Proteins Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Year: 2014 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hematopoietic Stem Cells / B-Lymphocytes / Gene Expression Regulation, Neoplastic / Lymphoma, Large B-Cell, Diffuse / DNA-Binding Proteins Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Year: 2014 Document type: Article