New predictive approaches for ITI treatment.

Minno, G D; Santagostino, E; Pratt, K; Königs, C

Minno, G D; Santagostino, E; Pratt, K; Königs, C.

Affiliation

Minno GD; Regional Reference Centre for Coagulation Disorders, Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy.

Haemophilia ; 20 Suppl 6: 27-43, 2014 Sep.

Article in En | MEDLINE | ID: mdl-24975702

Subject(s)

Coagulants/therapeutic use; Factor VIII/therapeutic use; Hemophilia A/drug therapy; Immune Tolerance/drug effects; B-Lymphocytes/immunology; Blood Coagulation Factor Inhibitors/immunology; Coagulants/antagonists & inhibitors; Factor VIII/antagonists & inhibitors; Factor VIII/genetics; Hemophilia A/immunology; Humans; Immune Tolerance/immunology; Italy; Mutation; Registries; T-Lymphocytes/immunology

Key words

B cell response; F8 mutations; T-cell response; anti-FVIII antibodies; immune tolerance induction therapy; thrombin generation assay

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Factor VIII / Coagulants / Hemophilia A / Immune Tolerance Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Country/Region as subject: Europa Language: En Journal: Haemophilia Year: 2014 Document type: Article

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