Hyperpolarized [1,3-13C2 ]ethyl acetoacetate is a novel diagnostic metabolic marker of liver cancer.

Jensen, Pernille R; Serra, Sonia Colombo; Miragoli, Luigi; Karlsson, Magnus; Cabella, Claudia; Poggi, Luisa; Venturi, Luca; Tedoldi, Fabio; Lerche, Mathilde H

Jensen, Pernille R; Serra, Sonia Colombo; Miragoli, Luigi; Karlsson, Magnus; Cabella, Claudia; Poggi, Luisa; Venturi, Luca; Tedoldi, Fabio; Lerche, Mathilde H.

Affiliation

Jensen PR; Albeda Research, Copenhagen, Denmark.

Int J Cancer ; 136(4): E117-26, 2015 Feb 15.

Article in En | MEDLINE | ID: mdl-25156718

Subject(s)

Acetoacetates; Contrast Media; Liver Neoplasms, Experimental/diagnosis; Acetoacetates/pharmacokinetics; Animals; Biomarkers, Tumor; Carboxylesterase/metabolism; Contrast Media/pharmacokinetics; Hep G2 Cells; Humans; Liver/metabolism; Liver Neoplasms, Experimental/metabolism; Neoplasm Transplantation; Rats, Inbred BUF; Signal-To-Noise Ratio

Key words

13C-DNP; carboxyl esterase; metabolism; tumor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Contrast Media / Liver Neoplasms, Experimental / Acetoacetates Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Int J Cancer Year: 2015 Document type: Article

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