TMEM14C is required for erythroid mitochondrial heme metabolism.

Yien, Yvette Y; Robledo, Raymond F; Schultz, Iman J; Takahashi-Makise, Naoko; Gwynn, Babette; Bauer, Daniel E; Dass, Abhishek; Yi, Gloria; Li, Liangtao; Hildick-Smith, Gordon J; Cooney, Jeffrey D; Pierce, Eric L; Mohler, Kyla; Dailey, Tamara A; Miyata, Non; Kingsley, Paul D; Garone, Caterina; Hattangadi, Shilpa M; Huang, Hui; Chen, Wen; Keenan, Ellen M; Shah, Dhvanit I; Schlaeger, Thorsten M; DiMauro, Salvatore; Orkin, Stuart H; Cantor, Alan B; Palis, James; Koehler, Carla M; Lodish, Harvey F; Kaplan, Jerry; Ward, Diane M; Dailey, Harry A; Phillips, John D; Peters, Luanne L; Paw, Barry H

Yien, Yvette Y; Robledo, Raymond F; Schultz, Iman J; Takahashi-Makise, Naoko; Gwynn, Babette; Bauer, Daniel E; Dass, Abhishek; Yi, Gloria; Li, Liangtao; Hildick-Smith, Gordon J; Cooney, Jeffrey D; Pierce, Eric L; Mohler, Kyla; Dailey, Tamara A; Miyata, Non; Kingsley, Paul D; Garone, Caterina; Hattangadi, Shilpa M; Huang, Hui; Chen, Wen; Keenan, Ellen M; Shah, Dhvanit I; Schlaeger, Thorsten M; DiMauro, Salvatore; Orkin, Stuart H; Cantor, Alan B; Palis, James; Koehler, Carla M; Lodish, Harvey F; Kaplan, Jerry; Ward, Diane M; Dailey, Harry A; Phillips, John D; Peters, Luanne L; Paw, Barry H.

J Clin Invest ; 124(10): 4294-304, 2014 Oct.

Article in En | MEDLINE | ID: mdl-25157825

Subject(s)

Erythropoiesis/genetics; Heme/metabolism; Mitochondria/metabolism; Mitochondrial Membrane Transport Proteins/metabolism; Anemia/metabolism; Animals; Cell Line; Erythroid Cells/metabolism; Gene Expression Regulation; Hemoglobins/metabolism; Liver/embryology; Membrane Proteins/genetics; Membrane Proteins/metabolism; Mice; Mitochondrial Membrane Transport Proteins/genetics; Mitochondrial Membranes/metabolism; Porphyrins/metabolism; Protoporphyrins/metabolism; RNA, Small Interfering/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitochondrial Membrane Transport Proteins / Erythropoiesis / Heme / Mitochondria Limits: Animals Language: En Journal: J Clin Invest Year: 2014 Document type: Article

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