Depletion of serotonin using p-chlorophenylalanine (PCPA) and reserpine protects against the neurotoxic effects of p-chloroamphetamine (PCA) in the brain.

Berger, U V; Grzanna, R; Molliver, M E

Berger, U V; Grzanna, R; Molliver, M E.

Affiliation

Berger UV; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.

Exp Neurol ; 103(2): 111-5, 1989 Feb.

Article in En | MEDLINE | ID: mdl-2521470

Subject(s)

Amphetamines/toxicity; Brain/metabolism; Fenclonine/pharmacology; Neurotoxins; Reserpine/pharmacology; Serotonin/metabolism; p-Chloroamphetamine/toxicity; Animals; Axons/drug effects; Axons/ultrastructure; Brain/drug effects; Brain/pathology; Male; Parietal Lobe/drug effects; Parietal Lobe/metabolism; Parietal Lobe/pathology; Rats; Rats, Inbred Strains; Reference Values

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Collection: 01-internacional Database: MEDLINE Main subject: P-Chloroamphetamine / Reserpine / Brain / Serotonin / Fenclonine / Amphetamines / Neurotoxins Limits: Animals Language: En Journal: Exp Neurol Year: 1989 Document type: Article

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