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Suppression of deacetylase SIRT1 mediates tumor-suppressive NOTCH response and offers a novel treatment option in metastatic Ewing sarcoma.
Ban, Jozef; Aryee, Dave N T; Fourtouna, Argyro; van der Ent, Wietske; Kauer, Max; Niedan, Stephan; Machado, Isidro; Rodriguez-Galindo, Carlos; Tirado, Oscar M; Schwentner, Raphaela; Picci, Piero; Flanagan, Adrienne M; Berg, Verena; Strauss, Sandra J; Scotlandi, Katia; Lawlor, Elizabeth R; Snaar-Jagalska, Ewa; Llombart-Bosch, Antonio; Kovar, Heinrich.
Affiliation
  • Ban J; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria.
  • Aryee DN; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria. Department of Pediatrics, Medical University of Vienna, Vienna, Austria.
  • Fourtouna A; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria.
  • van der Ent W; Institute of Biology and Department of Pathology, Leiden University, Leiden, The Netherlands.
  • Kauer M; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria.
  • Niedan S; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria.
  • Machado I; Department of Pathology, University Medical School, València, Spain.
  • Rodriguez-Galindo C; Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Tirado OM; Laboratori d'Oncología Molecular, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
  • Schwentner R; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria.
  • Picci P; Laboratory of Experimental Oncology, Rizzoli Institute, Bologna, Italy.
  • Flanagan AM; UCL Cancer Institute, University College London, London, United Kingdom.
  • Berg V; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria.
  • Strauss SJ; UCL Cancer Institute, University College London, London, United Kingdom.
  • Scotlandi K; Laboratory of Experimental Oncology, Rizzoli Institute, Bologna, Italy.
  • Lawlor ER; Translational Oncology Program, Departments of Pediatrics and Pathology, University of Michigan, Ann Arbor, Michigan.
  • Snaar-Jagalska E; Institute of Biology and Department of Pathology, Leiden University, Leiden, The Netherlands.
  • Llombart-Bosch A; Department of Pathology, University Medical School, València, Spain.
  • Kovar H; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria. Department of Pediatrics, Medical University of Vienna, Vienna, Austria. heinrich.kovar@ccri.at.
Cancer Res ; 74(22): 6578-88, 2014 Nov 15.
Article in En | MEDLINE | ID: mdl-25281719
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma, Ewing / Bone Neoplasms / Receptors, Notch / Sirtuin 1 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Res Year: 2014 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma, Ewing / Bone Neoplasms / Receptors, Notch / Sirtuin 1 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Res Year: 2014 Document type: Article