Worsening pneumonitis due to a pharmacokinetic drug-drug interaction between everolimus and voriconazole in a renal transplant patient.

Lecefel, C; Eloy, P; Chauvin, B; Wyplosz, B; Amilien, V; Massias, L; Taburet, A-M; Francois, H; Furlan, V

Lecefel, C; Eloy, P; Chauvin, B; Wyplosz, B; Amilien, V; Massias, L; Taburet, A-M; Francois, H; Furlan, V.

Affiliation

Lecefel C; Clinical Pharmacy, Bicetre Hospital, AP/HP, Le Kremlin Bicetre, France.

J Clin Pharm Ther ; 40(1): 119-20, 2015 Feb.

Article in En | MEDLINE | ID: mdl-25417855

Subject(s)

Antifungal Agents/adverse effects; Immunosuppressive Agents/adverse effects; Kidney Transplantation/adverse effects; Mycoses/prevention & control; Pneumonia/chemically induced; Sirolimus/analogs & derivatives; Voriconazole/adverse effects; Administration, Oral; Aged; Antifungal Agents/administration & dosage; Antifungal Agents/pharmacokinetics; Drug Interactions; Everolimus; Humans; Immunosuppressive Agents/administration & dosage; Immunosuppressive Agents/pharmacokinetics; Male; Mycoses/immunology; Sirolimus/administration & dosage; Sirolimus/adverse effects; Sirolimus/pharmacokinetics; Voriconazole/administration & dosage; Voriconazole/pharmacokinetics

Key words

everolimus; interaction; pneumonitis; transplantation; voriconazole

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Full text: 1 Collection: 01-internacional Health context: 4_TD Database: MEDLINE Main subject: Pneumonia / Kidney Transplantation / Sirolimus / Voriconazole / Immunosuppressive Agents / Mycoses / Antifungal Agents Limits: Aged / Humans / Male Language: En Journal: J Clin Pharm Ther Year: 2015 Document type: Article

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