Safety Study of Transcranial Static Magnetic Field Stimulation (tSMS) of the Human Cortex.
Brain Stimul
; 8(3): 481-5, 2015.
Article
in En
| MEDLINE
| ID: mdl-25595064
ABSTRACT
BACKGROUND:
Transcranial static magnetic field stimulation (tSMS) in humans reduces cortical excitability.OBJECTIVE:
The objective of this study was to determine if prolonged tSMS (2 h) could be delivered safely in humans. Safety limits for this technique have not been described.METHODS:
tSMS was applied for 2 h with a cylindric magnet on the occiput of 17 healthy subjects. We assessed tSMS-related safety aspects at tissue level by measuring levels of neuron-specific enolase (NSE, a marker of neuronal damage) and S100 (a marker of glial reactivity and damage). We also included an evaluation of cognitive side effects by using a battery of visuomotor and cognitive tests.RESULTS:
tSMS did not induce any significant increase in NSE or S100. No cognitive alteration was detected.CONCLUSIONS:
Our data indicate that the application of tSMS is safe in healthy human subjects, at least within these parameters.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cerebral Cortex
/
Transcranial Magnetic Stimulation
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Brain Stimul
Year:
2015
Document type:
Article