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Synthesis and characterization of 1'-C-cyano-2'-fluoro-2'-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.
Kirschberg, Thorsten A; Mish, Michael R; Zhang, Lijun; Squires, Neil H; Wang, Ke-Yu; Cho, Aesop; Feng, Joy Y; Fenaux, Martijn; Babusis, Darius; Park, Yeojin; Ray, Adrian S; Kim, Choung U.
Affiliation
  • Kirschberg TA; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
  • Mish MR; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
  • Zhang L; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
  • Squires NH; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
  • Wang KY; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
  • Cho A; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
  • Feng JY; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
  • Fenaux M; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
  • Babusis D; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
  • Park Y; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
  • Ray AS; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
  • Kim CU; Gilead Sciences, Inc., 333 Lakeside Drive, Foster City, CA 94044, USA.
Bioorg Med Chem Lett ; 25(5): 1040-3, 2015 Mar 01.
Article in En | MEDLINE | ID: mdl-25650256
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Pyrimidine Nucleosides / Hepacivirus Limits: Humans Language: En Journal: Bioorg Med Chem Lett Year: 2015 Document type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Pyrimidine Nucleosides / Hepacivirus Limits: Humans Language: En Journal: Bioorg Med Chem Lett Year: 2015 Document type: Article