von Willebrand factor arginine 1205 substitution results in accelerated macrophage-dependent clearance in vivo.

Rawley, O; O'Sullivan, J M; Chion, A; Keyes, S; Lavin, M; van Rooijen, N; Brophy, T M; Fallon, P; Preston, R J S; O'Donnell, J S

Rawley, O; O'Sullivan, J M; Chion, A; Keyes, S; Lavin, M; van Rooijen, N; Brophy, T M; Fallon, P; Preston, R J S; O'Donnell, J S.

Affiliation

Rawley O; Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital, Trinity College Dublin, Dublin, Ireland.

J Thromb Haemost ; 13(5): 821-6, 2015 May.

Article in En | MEDLINE | ID: mdl-25690668

Subject(s)

Arginine/chemistry; Macrophages/physiology; von Willebrand Factor/physiology; Animals; Mice; Mice, Knockout; von Willebrand Factor/chemistry

Key words

glycosylation; metabolic clearance rate; von Willebrand disease, Type 1; von Willebrand disease, Type 2; von Willebrand factor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arginine / Von Willebrand Factor / Macrophages Limits: Animals Language: En Journal: J Thromb Haemost Year: 2015 Document type: Article

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