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Distinct Commensals Induce Interleukin-1ß via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury.
Seo, Sang-Uk; Kamada, Nobuhiko; Muñoz-Planillo, Raúl; Kim, Yun-Gi; Kim, Donghyun; Koizumi, Yukiko; Hasegawa, Mizuho; Himpsl, Stephanie D; Browne, Hilary P; Lawley, Trevor D; Mobley, Harry L T; Inohara, Naohiro; Núñez, Gabriel.
Affiliation
  • Seo SU; Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
  • Kamada N; Division of Gastroenterology, Department of Internal Medicine, The University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
  • Muñoz-Planillo R; Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
  • Kim YG; Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
  • Kim D; Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
  • Koizumi Y; Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
  • Hasegawa M; Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
  • Himpsl SD; Department of Microbiology and Immunology, The University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
  • Browne HP; Bacterial Pathogenesis Laboratory, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
  • Lawley TD; Bacterial Pathogenesis Laboratory, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
  • Mobley HL; Department of Microbiology and Immunology, The University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
  • Inohara N; Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.
  • Núñez G; Department of Pathology and Comprehensive Cancer Center, The University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address: gabriel.nunez@umich.edu.
Immunity ; 42(4): 744-55, 2015 Apr 21.
Article in En | MEDLINE | ID: mdl-25862092
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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Symbiosis / Monocytes / Carrier Proteins / Interleukin-1beta / Inflammasomes / Microbiota Language: En Journal: Immunity Year: 2015 Document type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Symbiosis / Monocytes / Carrier Proteins / Interleukin-1beta / Inflammasomes / Microbiota Language: En Journal: Immunity Year: 2015 Document type: Article