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Pan-cancer analysis of genomic scar signatures associated with homologous recombination deficiency suggests novel indications for existing cancer drugs.
Marquard, Andrea M; Eklund, Aron C; Joshi, Tejal; Krzystanek, Marcin; Favero, Francesco; Wang, Zhigang C; Richardson, Andrea L; Silver, Daniel P; Szallasi, Zoltan; Birkbak, Nicolai J.
Affiliation
  • Marquard AM; Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Kemitorvet 8, 2800 Lyngby, Denmark.
  • Eklund AC; Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Kemitorvet 8, 2800 Lyngby, Denmark.
  • Joshi T; Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Kemitorvet 8, 2800 Lyngby, Denmark.
  • Krzystanek M; Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Kemitorvet 8, 2800 Lyngby, Denmark.
  • Favero F; Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Kemitorvet 8, 2800 Lyngby, Denmark.
  • Wang ZC; Department of Cancer Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, 02215 Boston, Massachusetts USA.
  • Richardson AL; Department of Surgery, Brigham and Women's Hospital, 75 Francis Street, 02115 Boston, Massachusetts USA.
  • Silver DP; Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, 02115 Boston, Massachusetts USA.
  • Szallasi Z; Department of Cancer Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, 02215 Boston, Massachusetts USA.
  • Birkbak NJ; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, 02215 Boston, Massachusetts USA.
Biomark Res ; 3: 9, 2015.
Article in En | MEDLINE | ID: mdl-26015868
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Biomark Res Year: 2015 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Biomark Res Year: 2015 Document type: Article