Thermodynamics and kinetic studies in the binding interaction of cyclic naphthalene diimide derivatives with double stranded DNAs.

Islam, Md Monirul; Fujii, Satoshi; Sato, Shinobu; Okauchi, Tatsuo; Takenaka, Shigeori

Islam, Md Monirul; Fujii, Satoshi; Sato, Shinobu; Okauchi, Tatsuo; Takenaka, Shigeori.

Affiliation

Islam MM; Department of Applied Chemistry, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan.
Fujii S; Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Iizuka, Fukuoka 820-8502, Japan.
Sato S; Department of Applied Chemistry, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan.
Okauchi T; Department of Applied Chemistry, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan.
Takenaka S; Department of Applied Chemistry, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan. Electronic address: shige@che.kyutech.ac.jp.

Bioorg Med Chem ; 23(15): 4769-4776, 2015 Aug 01.

Article in En | MEDLINE | ID: mdl-26081762

Subject(s)

DNA/chemistry; Imides/chemistry; Naphthalenes/chemistry; Animals; Cattle; Circular Dichroism; DNA/metabolism; DNA Topoisomerases, Type I/metabolism; Imides/metabolism; Kinetics; Naphthalenes/metabolism; Polydeoxyribonucleotides/chemistry; Polydeoxyribonucleotides/metabolism; Spectrophotometry, Ultraviolet; Thermodynamics

Key words

Bis-intercalative binding; Cyclic naphthalene diimide derivatives; Double-stranded DNA; Entropy-dependence binding; Hydrophobic interaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Imides / Naphthalenes Limits: Animals Language: En Journal: Bioorg Med Chem Year: 2015 Document type: Article

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