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High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells.
Pera, Benet; Calvo-Vidal, M Nieves; Ambati, Srikanth; Jordi, Michel; Kahn, Alissa; Díaz, J Fernando; Fang, Weishuo; Altmann, Karl-Heinz; Cerchietti, Leandro; Moore, Malcolm A S.
Affiliation
  • Pera B; Department of Medicine, Weill Cornel Medical College, 1300 York Avenue, New York, NY 10065, United States.
  • Calvo-Vidal MN; Department of Medicine, Weill Cornel Medical College, 1300 York Avenue, New York, NY 10065, United States.
  • Ambati S; Department of Cell Biology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, United States.
  • Jordi M; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zürich, HCI H405, Vladimir-Prelog-Weg 4, 8093 Zürich, Switzerland.
  • Kahn A; Department of Cell Biology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, United States.
  • Díaz JF; Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Ramiro de Maeztu 9, 28040 Madrid, Spain.
  • Fang W; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, 2A Nan Wei Road, Beijing 100050, China.
  • Altmann KH; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, Swiss Federal Institute of Technology (ETH) Zürich, HCI H405, Vladimir-Prelog-Weg 4, 8093 Zürich, Switzerland.
  • Cerchietti L; Department of Medicine, Weill Cornel Medical College, 1300 York Avenue, New York, NY 10065, United States. Electronic address: lec2010@med.cornell.edu.
  • Moore MAS; Department of Cell Biology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, United States.
Cancer Lett ; 368(1): 97-104, 2015 Nov 01.
Article in En | MEDLINE | ID: mdl-26277539

Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Antineoplastic Combined Chemotherapy Protocols / Paclitaxel / Macrolides / Drug Resistance, Neoplasm / Tubulin Modulators / Microtubules Limits: Animals / Humans Language: En Journal: Cancer Lett Year: 2015 Document type: Article

Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Antineoplastic Combined Chemotherapy Protocols / Paclitaxel / Macrolides / Drug Resistance, Neoplasm / Tubulin Modulators / Microtubules Limits: Animals / Humans Language: En Journal: Cancer Lett Year: 2015 Document type: Article