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Rational design of stable and functional hirudin III mutants with lower antigenicity.
Asgari, Saeme; Mirzahoseini, Hasan; Karimipour, Morteza; Rahimi, Hamze; Ebrahim-Habibi, Azadeh.
Affiliation
  • Asgari S; Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
  • Mirzahoseini H; Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran. Electronic address: mirzahoseini@pasteur.ac.ir.
  • Karimipour M; Molecular Medicine Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
  • Rahimi H; Molecular Medicine Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
  • Ebrahim-Habibi A; Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, I
Biologicals ; 43(6): 479-91, 2015 Nov.
Article in En | MEDLINE | ID: mdl-26321653
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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Hirudins / Point Mutation / Computational Biology / Mutation, Missense / Hirudo medicinalis / Epitopes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Biologicals Year: 2015 Document type: Article
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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Hirudins / Point Mutation / Computational Biology / Mutation, Missense / Hirudo medicinalis / Epitopes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Biologicals Year: 2015 Document type: Article