Species and sex differences in propofol glucuronidation in liver microsomes of humans, monkeys, rats and mice.

Mukai, M; Isobe, T; Okada, K; Murata, M; Shigeyama, M; Hanioka, N

Mukai, M; Isobe, T; Okada, K; Murata, M; Shigeyama, M; Hanioka, N.

Pharmazie ; 70(7): 466-70, 2015 Jul.

Article in En | MEDLINE | ID: mdl-26373207

Subject(s)

Anesthetics, Intravenous/pharmacokinetics; Microsomes, Liver/metabolism; Propofol/pharmacokinetics; Adult; Aged; Animals; Female; Glucuronides/metabolism; Humans; Macaca fascicularis; Male; Mice; Middle Aged; Rats; Rats, Wistar; Sex Characteristics; Species Specificity; Young Adult

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Collection: 01-internacional Database: MEDLINE Main subject: Microsomes, Liver / Propofol / Anesthetics, Intravenous Type of study: Prognostic_studies Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Pharmazie Year: 2015 Document type: Article

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