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Genome-wide autozygosity is associated with lower general cognitive ability.
Howrigan, D P; Simonson, M A; Davies, G; Harris, S E; Tenesa, A; Starr, J M; Liewald, D C; Deary, I J; McRae, A; Wright, M J; Montgomery, G W; Hansell, N; Martin, N G; Payton, A; Horan, M; Ollier, W E; Abdellaoui, A; Boomsma, D I; DeRosse, P; Knowles, E E M; Glahn, D C; Djurovic, S; Melle, I; Andreassen, O A; Christoforou, A; Steen, V M; Hellard, S L; Sundet, K; Reinvang, I; Espeseth, T; Lundervold, A J; Giegling, I; Konte, B; Hartmann, A M; Rujescu, D; Roussos, P; Giakoumaki, S; Burdick, K E; Bitsios, P; Donohoe, G; Corley, R P; Visscher, P M; Pendleton, N; Malhotra, A K; Neale, B M; Lencz, T; Keller, M C.
Affiliation
  • Howrigan DP; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Simonson MA; Stanley Center for Psychiatric Genetics, Broad Institute of Harvard and MIT, Cambridge Center, Cambridge, MA, USA.
  • Davies G; Division of Data Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Harris SE; Department of Psychology, University of Edinburgh, Edinburgh, UK.
  • Tenesa A; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
  • Starr JM; Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.
  • Liewald DC; Institute of Genetics and Molecular Medicine, MRC Human Genetics Unit, Western General Hospital, University of Edinburgh, Edinburgh, UK.
  • Deary IJ; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, UK.
  • McRae A; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
  • Wright MJ; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK.
  • Montgomery GW; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
  • Hansell N; Department of Psychology, University of Edinburgh, Edinburgh, UK.
  • Martin NG; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.
  • Payton A; Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.
  • Horan M; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.
  • Ollier WE; Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.
  • Abdellaoui A; Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.
  • Boomsma DI; Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.
  • DeRosse P; Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.
  • Knowles EE; Centre for Integrated Genomic Medical Research, Institute of Population Health, University of Manchester, Manchester, UK.
  • Glahn DC; Centre for Clinical and Cognitive Neurosciences, Institute of Brain Behaviour and Mental Health, University of Manchester, Salford Royal NHS Foundation Trust, Salford, UK.
  • Djurovic S; Centre for Integrated Genomic Medical Research, Institute of Population Health, University of Manchester, Manchester, UK.
  • Melle I; Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands.
  • Andreassen OA; Neuroscience Campus Amsterdam, Amsterdam, The Netherlands.
  • Christoforou A; Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands.
  • Steen VM; Neuroscience Campus Amsterdam, Amsterdam, The Netherlands.
  • Hellard SL; EMGO+ Institute for Health and Care Research, Amsterdam, The Netherlands.
  • Sundet K; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA.
  • Reinvang I; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA.
  • Espeseth T; Hofstra North Shore - LIJ School of Medicine, Departments of Psychiatry and Molecular Medicine, Hempstead, NY, USA.
  • Lundervold AJ; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
  • Giegling I; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
  • Konte B; NORMENT, KG Jebsen Centre, Oslo, Norway.
  • Hartmann AM; Oslo University Hospital, Oslo, Norway.
  • Rujescu D; NORMENT, KG Jebsen Centre, Oslo, Norway.
  • Roussos P; Oslo University Hospital, Oslo, Norway.
  • Giakoumaki S; University of Oslo, Oslo, Norway.
  • Burdick KE; NORMENT, KG Jebsen Centre, Oslo, Norway.
  • Bitsios P; Oslo University Hospital, Oslo, Norway.
  • Donohoe G; University of Oslo, Oslo, Norway.
  • Corley RP; K.G. Jebsen Centre for Psychosis Research, Dr. Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
  • Visscher PM; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.
  • Pendleton N; K.G. Jebsen Centre for Psychosis Research, Dr. Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
  • Malhotra AK; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.
  • Neale BM; K.G. Jebsen Centre for Psychosis Research, Dr. Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
  • Lencz T; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.
  • Keller MC; NORMENT, KG Jebsen Centre, Oslo, Norway.
Mol Psychiatry ; 21(6): 837-43, 2016 06.
Article in En | MEDLINE | ID: mdl-26390830
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cognition / Inbreeding Depression Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Mol Psychiatry Year: 2016 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cognition / Inbreeding Depression Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Mol Psychiatry Year: 2016 Document type: Article