Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.
Clin Pharmacol Ther
; 99(2): 172-85, 2016 Feb.
Article
in En
| MEDLINE
| ID: mdl-26479518
ABSTRACT
This article provides nomenclature recommendations developed by an international workgroup to increase transparency and standardization of pharmacogenetic (PGx) result reporting. Presently, sequence variants identified by PGx tests are described using different nomenclature systems. In addition, PGx analysis may detect different sets of variants for each gene, which can affect interpretation of results. This practice has caused confusion and may thereby impede the adoption of clinical PGx testing. Standardization is critical to move PGx forward.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pharmacogenetics
/
Genetic Testing
/
Alleles
/
Terminology as Topic
Type of study:
Guideline
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Clin Pharmacol Ther
Year:
2016
Document type:
Article