Optimizing DMPK Properties: Experiences from a Big Pharma DMPK Department.

Sohlenius-Sternbeck, Anna-Karin; Janson, Juliette; Bylund, Johan; Baranczewski, Pawel; Breitholtz-Emanuelsson, Anna; Hu, Yin; Tsoi, Carrie; Lindgren, Anders; Gissberg, Olle; Bueters, Tjerk; Briem, Sveinn; Juric, Sanja; Johansson, Jenny; Bergh, Margareta; Hoogstraate, Janet

Sohlenius-Sternbeck, Anna-Karin; Janson, Juliette; Bylund, Johan; Baranczewski, Pawel; Breitholtz-Emanuelsson, Anna; Hu, Yin; Tsoi, Carrie; Lindgren, Anders; Gissberg, Olle; Bueters, Tjerk; Briem, Sveinn; Juric, Sanja; Johansson, Jenny; Bergh, Margareta; Hoogstraate, Janet.

Affiliation

Sohlenius-Sternbeck AK; DMPK & Bioanalysis, Medivir AB, SE-141 44 Huddinge, Sweden. annakarin.sternbeck@gmail.com.

Curr Drug Metab ; 17(3): 253-70, 2016.

Article in En | MEDLINE | ID: mdl-26651977

Subject(s)

Drug Discovery; Pharmaceutical Preparations/metabolism; Pharmacokinetics; Animals; Blood Proteins/metabolism; Drug Industry; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Glutathione/metabolism; Humans; Permeability; Pharmaceutical Preparations/chemistry; Protein Binding

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Collection: 01-internacional Database: MEDLINE Main subject: Pharmacokinetics / Pharmaceutical Preparations / Drug Discovery Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Curr Drug Metab Year: 2016 Document type: Article

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