Perinatal citalopram does not prevent the effect of prenatal stress on anxiety, depressive-like behaviour and serotonergic transmission in adult rat offspring.

Zohar, Inbar; Shoham, Shai; Weinstock, Marta

Zohar, Inbar; Shoham, Shai; Weinstock, Marta.

Affiliation

Zohar I; Department of Pharmacology, Institute of Drug Research, Hebrew University Medical Centre, Ein Kerem, Jerusalem, Israel.
Shoham S; Department of Pharmacology, Institute of Drug Research, Hebrew University Medical Centre, Ein Kerem, Jerusalem, Israel.
Weinstock M; Department of Pharmacology, Institute of Drug Research, Hebrew University Medical Centre, Ein Kerem, Jerusalem, Israel.

Eur J Neurosci ; 43(4): 590-600, 2016 Feb.

Article in En | MEDLINE | ID: mdl-26669896

Subject(s)

Anxiety/drug therapy; Citalopram/pharmacology; Prefrontal Cortex/drug effects; Selective Serotonin Reuptake Inhibitors/pharmacology; Animals; Autoreceptors/metabolism; Behavior, Animal/drug effects; Corticotropin-Releasing Hormone/metabolism; Disease Models, Animal; Female; Prefrontal Cortex/metabolism; Prefrontal Cortex/physiopathology; Pregnancy; Rats, Wistar; Serotonin/metabolism; Stress, Physiological

Key words

corticotropin-releasing factor type 2 receptors; dorsal raphe nuclei; medial prefrontal cortex; serotonin 1A autoreceptors; tryptophan hydroxylase

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anxiety / Citalopram / Selective Serotonin Reuptake Inhibitors / Prefrontal Cortex Type of study: Prognostic_studies Limits: Animals / Pregnancy Language: En Journal: Eur J Neurosci Year: 2016 Document type: Article

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