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Analysis of a four generation family reveals the widespread sequence-dependent maintenance of allelic DNA methylation in somatic and germ cells.
Tang, Aifa; Huang, Yi; Li, Zesong; Wan, Shengqing; Mou, Lisha; Yin, Guangliang; Li, Ning; Xie, Jun; Xia, Yudong; Li, Xianxin; Luo, Liya; Zhang, Junwen; Chen, Shen; Wu, Song; Sun, Jihua; Sun, Xiaojuan; Jiang, Zhimao; Chen, Jing; Li, Yingrui; Wang, Jian; Wang, Jun; Cai, Zhiming; Gui, Yaoting.
Affiliation
  • Tang A; Shenzhen Key Laboratory of Genitourinary Tumor, National-Regional Key Engineering Technology Laboratory for Clinical Application of Cancer Genomics, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China.
  • Huang Y; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, China.
  • Li Z; Shenzhen Key Laboratory of Genitourinary Tumor, National-Regional Key Engineering Technology Laboratory for Clinical Application of Cancer Genomics, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China.
  • Wan S; The Genome Institute, Washington University in St Louis, Missouri 63108, USA.
  • Mou L; Shenzhen Key Laboratory of Genitourinary Tumor, National-Regional Key Engineering Technology Laboratory for Clinical Application of Cancer Genomics, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China.
  • Yin G; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, China.
  • Li N; Luohu People's Hospital, Shezhen 518001, China.
  • Xie J; Shenzhen Key Laboratory of Genitourinary Tumor, National-Regional Key Engineering Technology Laboratory for Clinical Application of Cancer Genomics, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China.
  • Xia Y; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, China.
  • Li X; BGI-Shenzhen, Shenzhen 518083, China.
  • Luo L; BGI-Shenzhen, Shenzhen 518083, China.
  • Zhang J; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, China.
  • Chen S; BGI-Shenzhen, Shenzhen 518083, China.
  • Wu S; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, China.
  • Sun J; Shenzhen Key Laboratory of Genitourinary Tumor, National-Regional Key Engineering Technology Laboratory for Clinical Application of Cancer Genomics, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China.
  • Sun X; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, China.
  • Jiang Z; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, China.
  • Chen J; Shenzhen Key Laboratory of Genitourinary Tumor, National-Regional Key Engineering Technology Laboratory for Clinical Application of Cancer Genomics, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China.
  • Li Y; The Genome Institute, Washington University in St Louis, Missouri 63108, USA.
  • Wang J; Luohu People's Hospital, Shezhen 518001, China.
  • Wang J; BGI-Shenzhen, Shenzhen 518083, China.
  • Cai Z; Shenzhen Key Laboratory of Genitourinary Tumor, National-Regional Key Engineering Technology Laboratory for Clinical Application of Cancer Genomics, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen 518035, China.
  • Gui Y; Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, China.
Sci Rep ; 6: 19260, 2016 Jan 13.
Article in En | MEDLINE | ID: mdl-26758766
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Family / DNA Methylation / Epigenesis, Genetic / Alleles / Germ Cells Limits: Humans / Male Language: En Journal: Sci Rep Year: 2016 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Family / DNA Methylation / Epigenesis, Genetic / Alleles / Germ Cells Limits: Humans / Male Language: En Journal: Sci Rep Year: 2016 Document type: Article