A case of dysgraphia induced by sertraline and a review of official spontaneous adverse reaction databases.
J Clin Pharm Ther
; 41(1): 106-7, 2016 Feb.
Article
in En
| MEDLINE
| ID: mdl-26792111
ABSTRACT
WHAT IS KNOWN AND OBJECTIVES:
The occurrence of dysgraphia after sertraline intake has never been reported. The objective was to describe a case of this adverse drug reaction and present a review of similar cases held in international databases with a discussion of the possible pharmacological mechanisms. CASESUMMARY:
We observed a 60-year-old man who experienced resting tremors, dyskinesia and dysgraphia 2 months after a stepwise increase in sertraline dosing from 50 to 200 mg/day. WHAT IS NEW ANDCONCLUSION:
Dysgraphia is a possible adverse drug reaction to sertraline, and we suggest that inhibition of extrapyramidal dopaminergic activity might be the pharmacological mechanism.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Selective Serotonin Reuptake Inhibitors
/
Sertraline
/
Agraphia
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Clin Pharm Ther
Year:
2016
Document type:
Article