[Two Cases of Pathological Complete Response with Neoadjuvant Therapy for Advanced Rectal Cancer].
Gan To Kagaku Ryoho
; 42(12): 2313-5, 2015 Nov.
Article
in Ja
| MEDLINE
| ID: mdl-26805348
ABSTRACT
We report the cases of 2 patients with advanced rectal cancer who achieved pathological complete response to treatment with preoperative therapy. Case 1 was a 72-year-old man diagnosed with cT3N1M0 advanced rectal cancer. Neoadjuvant chemoradiotherapy with S-1 (120 mg/day) and radiation (50 Gy/25 Fr) was administered. Eight weeks after the last chemoradiation therapy, we performed laparoscopic Hartmann's operation. Case 2 was a 59-year-old man diagnosed with cT4aN0M0 advanced rectal cancer. He was treated with XELOX plus bevacizumab as neoadjuvant chemotherapy. Four weeks after 4 courses of treatment, he underwent laparoscopic Mile's operation. Neoadjuvant therapy was performed without any complications, and a pathological complete response was achieved in both patients. These cases demonstrated that neoadjuvant therapy can be a promising option for locally advanced rectal cancer.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rectal Neoplasms
/
Neoadjuvant Therapy
Limits:
Aged
/
Humans
/
Male
/
Middle aged
Language:
Ja
Journal:
Gan To Kagaku Ryoho
Year:
2015
Document type:
Article